Transposable element invasions

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Transposable element invasions

Transposable elements have an ongoing, largely parasitic interaction with their hosts. We are interested in the timescale of this interaction. In a recent publication, we have examined the sequence divergence between class II DNA transposons from mammalian genomes. We asked whether these sequences undergo a continuing process of turnover, keeping a family as an integrated whole, as members of t...

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Transposable element distributions in Drosophila.

S URVEYS of transposable elements (TEs) in populations of Drosophila melanogaster have shown that the frequencies of elements at individual sites within the genome are nearly always very low. Detailed statistical studies of element distributions indicate that selection must be acting to oppose the transpositional spread of elements (CHARLESWORTH and LANGLEY 1991; BIEMONT 1992). While this concl...

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Transposable Element Exaptation in Plants

While evolution is often understood exclusively in terms of adaptation, innovation often begins when a feature adapted for one function is co-opted for a different purpose, such aswhen feathers originally adapted for insulation became used for flight. Co-opted features are called exaptations. Transposable elements are often viewed as molecular parasites, yet they are frequently the source of ev...

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Inference of Transposable Element Ancestry

Most common methods for inferring transposable element (TE) evolutionary relationships are based on dividing TEs into subfamilies using shared diagnostic nucleotides. Although originally justified based on the "master gene" model of TE evolution, computational and experimental work indicates that many of the subfamilies generated by these methods contain multiple source elements. This implies t...

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PIWI proteins and PIWI-interacting RNAs (piRNAs) are part of a cellular pathway that has evolved to protect genomes against the proliferation of transposable elements (TEs). PIWIs and piRNAs assemble into complexes that are involved in epigenetic and post-transcriptional repression of TEs. Most of our understanding of the mechanisms of piRNA-mediated TE silencing comes from fruit fly and mouse ...

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ژورنال

عنوان ژورنال: Mobile Genetic Elements

سال: 2013

ISSN: 2159-256X

DOI: 10.4161/mge.23920